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Stabilization of fatty acid synthesis enzyme acetyl-CoA carboxylase 1 suppresses acute myeloid leukemia development

Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes

(2019) 60:E15

Increased membrane cholesterol content lowers the activation threshold of T cells, a key mechanism underlying T cell hyperactivation in SLE patients (61, 62)

Significant body weight reductions were observed in all studies except that of Horne et al., which only identified significant changes in galectin-3 levels (27)