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Possibly, this toxicity, in addition to lower esophageal sphincter and pyloric sphincter failure, involves sole NSAIDs-gastric ulcers, presenting with aspirin (and thereby, aspirin was used intragastrically) (14) and ibuprofen (10), as well as with those agents combining gastric and small intestine ulcers (i.e., diclofenac (9, 11))

Neuroscience 298 , 1225 (2015)

Copper-free GHK can chelate copper from surrounding media or biological fluids, making its effects dependent on ambient copper availability, which introduces an uncontrolled variable in experimental systems

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