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10.1002/(SICI)1096-9896(200004)190:5 3.0.CO;2-9

R.ChenA.DavisH

doi: 10.3390/ijms18051051 24 SidoBSeelCHochlehnertABreitkreutzRDrogeW

This calculation assumed intra-subject coefficients of variation of approximately 12% for AUC and 17% for C max , based on earlier studies with the FD formulation and values between 0.95 and 1.05 for the true treatment ratio test/reference