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Although tadalafil has received approval from the FDA as a commercial medication for the treatment of ED, BPH, and PAH, it might be used cautiously in subjects at high risk of cerebrovascular ischemic events

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In this non-placebo-controlled trial, eGFR statistically increased after 4 and 8 weeks compared with baseline (2.8 mL/min/1.73 m 2 and 7.2 mL/min/1.73 m 2 at each time point, respectively) [55]

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Annu Rev Immunol 39:279311

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