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Its not a medication, and its not approved for human or animal use outside of authorized studies 5-Amino-1MQ is a small-molecule research compound supplied for in-vitro investigation into metabolic and enzymatic signaling pathways, particularly through its activity as an inhibitor of nicotinamide N-methyltransferase (NNMT)

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A structural explanation for these findings was provided from our previous cryo-EM structures of CT(Pro32) and rAmy(Tyr37)-bound AMYRs structures where the bulky phenolic side chain of Y37 rAmy forms perpendicular stacking interactions with W79 ECD 15 , and additional interactions with the respective RAMP protomer that are likely important for selectivity of rAmy for AMYRs over CTR

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