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Carotenoids react with LOO at conjugated double bonds, producing a radical adduct (LOO-CAR ) that undergoes resonance stabilization at low oxygen pressure, favouring the chain-termination reaction over the chain-propagation reaction [151]

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246,248 LTB 4 can enhance neutrophil accumulation in acute inflammation or injury by directly recruiting neutrophils through BLT1, or by serving as a relay signal that sustains a chemotactic gradient, guiding neutrophil migration toward other chemoattractants, including formyl peptides or C5a