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Many practitioners promote them for their ability to hydrate the skin and offer a more shining look, further driving their popularity

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However, in a double-blind, placebo-controlled phase II trial of TSO in adults with active Crohns disease (n = 252), ingestion of 250-7500 TSO fortnightly over 12 weeks was observed to be safe without any adverse effects, but the treatment did not have an advantage over the placebo in inducing clinical remission and other immunological responses (Scholmerich et al., 2017)

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