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Mechanisms of action of KD in neurodegeneration The classical KD is a high-fat, low-carbohydrate, and adequate-protein dietary regimen designed to mimic the metabolic effects of fasting without significant calorie restriction, thereby promoting an anabolic state [23]

Polymorphism of GSTA1 is represented by three linked single nucleotide polymorphisms (SNPs), resulting in differential expression with lower transcriptional activation of the variant GSTA1 * B (T) than the common GSTA1*A (C) allele 33

10.1371/journal.pone.0218533 88 HickmanI.JonssonJ.PrinsJ.AshS.PurdieD.CloustonA.et al (2004)

The chemical behavior of sulfides contrasts with that of ethers in some important ways

Notably, the efficacy of these strategies may vary among individuals, and seeking individualised advice from healthcare professionals is recommended