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Cigarette smoke, a typical form of organic exposure, accelerates neurodegenerative processes, including increased AD-associated A deposition and PD-characteristic -synuclein aggregation in the substantia nigra [162]

Oxidative stress, which can damage cells, proteins, and DNA, is associated with various health conditions

In rat depressive model induced by chronic mild stress, Cdk5 activity and p35 trafficking was enhanced in the hippocampal dentate gyrus, which was suppressed by the antidepressant venlafaxine (Zhu et al., 2012)