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Results from a randomised double-blind placebo controlled study showed the initiation of early caffeine did not reduce the age of first successful extubation, rates of BPD, or the duration of need for supplemental oxygen when compared with the placebo group and this trial was halted due to a non-significant trend towards an increased mortality rate in the caffeine group (97)

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Discussion Dadachamame, from Tsuruoka in Yamagata Prefecture, Japan, showed higher levels of FAA and sucrose than the prevalent soybean cultivar from the early seed formation stage (R5) through the edamame stage (R6) (Fig