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These aggregates compromise cell viability by indiscriminately trapping diverse proteins, including Syn

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Kon T, Ueno T, Haga R, Tomiyama M

Cardiovasc Hematol Disord Drug Targets (2014) 14(1):2233

The individual silencing of TPK1 or each of the TPP carriers Slc25a19 and Slc19a3 in neurons significantly decreased dendrite arborization and soma size compared to controls (100)