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You may be vitamin B deficient if you experience some or all of the following unexplained symptoms: Skin cracks around the mouth Scaly lip skin Skin rashes Fatigue Anemia Depression or irritability Confusion Diarrhea or constipation Abdominal cramps Tingling or numbness in your feet and hands Vitamin B12 deficiency is particularly serious, as it increases your risk for neuropsychiatric disorders

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The answer depends on what kind of vial you have, how it was made, whether it has been opened, how you store it, and what formulation sits inside that glass container

Diabetes Res Clin Pract 183:109119

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