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When the substance has been injected, people have reported that they experience cramping and burning at the injection site

The pressure release that causes the sudden leakage of filler from the syringe is often caused by: A loose needle attachment Poor manufacturing tolerances between the needle and syringe Excessive injection pressure Reusing or manipulating prefilled syringes Incompatible needle changes

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7.2 Safety data from clinical studies Current studies indicate that both NSP inhibitory effects and skin symptom occurrence require high levels of DPP1 inhibition (Turk et al., 2001)