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This idea is demonstrated by Figure 1 which compares the NMR solution structures of several IDPs serving as illustrations of the blurry view of IDP conformational ensembles from low-resolution methods with the crisp view of ordered proteins generated by high-resolution methods, such as X-ay crystallography and NMR

Trismus (lockjaw): TMD can be both a cause and a symptom of this condition, in which the jaw muscles spasm and the jaw cannot fully open

On clinical examination, there is often difficulty with or pain on squatting or climbing stairs3

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