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(2023) 37:e23037

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway

SIRT1 reverses senescence via enhancing autophagy and attenuates oxidative stress-induced apoptosis through promoting p53 degradation

These agents converge on key regulatory nodes: The AMPK/mTOR axis and the Sestrin-2/LKB1/AMPK cascade to provoke autophagy and cell death (95-97)

55,68,69 Anti-integrin The anti-integrin antibody, vedolizumab, is indicated for moderate to severe UC when the response to immunomodulator therapy is inadequate