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DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer

In line with these findings, a potential toxic synergism between APAP and salicylates (e.g., aspirin) can result in liver failure, particularly in children, potentiated by the exhaustion of GSH levels (Nourjah et al., 2006) with a mortality rate of approximately 0.4% (450 deaths a year) in the United States (Yoon et al., 2016)

NAC can theoretically tackle neurotransmitter imbalance, oxidative stress, and neuroinflammation making it a logical candidate drug for these conditions ( 16 )