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Description

The study was supported by the Ministry of Science and Technology of the Peoples Republic of China (2024ZD0525600 to Yu Wang), the National Natural Science Foundation of China (82473361 to Yu Wang, 82203052 to Ben Ma), the Science and Technology Commission of Shanghai Municipality (22Y21900100 to Yu Wang), the Shanghai Anticancer Association (SACA-AX202213 to Yu Wang), the Shanghai Municipal Health Commission (20234Y0120 to Ben Ma)

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High-resolution damage mapping achieves single-nucleotide level precision (70)

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Mechanism of Toxicity 23-28 Pathophysiology: Inhibition of Acetylcholinesterase (AChE) The primary mechanism underlying organophosphate (OP) toxicity is the irreversible inhibition of the enzyme acetylcholinesterase (AChE), which is responsible for hydrolyzing the neurotransmitter acetylcholine (ACh) into acetate and choline at cholinergic synapses

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Lesuisse E, Knight SA, Camadro JM, Dancis A

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: : 1-2 TATIONIL 600

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