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Additionally, a recent observational study reports that metformin may enhance antitumor immunity and improve prognosis in patients with upfront resected PDAC, but not in patients with gemcitabine-based neoadjuvant chemoradiotherapy [114]

Research of Interest These two articles were produced by individuals associated with the IAOMT, and the articles are available for you to read in their entirety: Duplinsky TG, Cicchetti DV

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The robust anti-cancer properties of UA are ascribed to its capacity to suppress tumor cell proliferation, facilitate apoptosis, induce cellular autophagy, and specifically target drug-resistant cancer cells [1034, 1035]