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By increasing selenoprotein synthesis and thereby suppressing CRP production, Se supplementation can compensate for lower levels of Se in serum and liver, and as a result, inflammation will be attenuated [50] Although Se supplementation with sodium selenite decreased CRP levels in acute respiratory distress syndrome (ARDS) patients during the study period, the differences between Se-supplemented and control groups were not significant [51]

Changes in Fatty Acid Profiles of Plasma, Erythrocytes and Polymorphonuclear Leukocytes in Induced Hypothyroidism in Man: Indirect Evidence for Altered Delta 6 Desaturase Activity

Siemieniuk RA, Bartoszko JJ, Ge L, et al

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