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Interestingly, some of these disorders also occur as acquired syndromes, in the course of myelodysplastic syndromes and acute leukemia

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[166] Research has shown that the accumulation of intracellular lactate increases the lactylation of histones at HIF-1 targets (such as BMP5, TRPC5, and KIT), thereby influencing PASMC proliferation [184]

Brenda Johnson, MATS, PA-C, explores the four primary forms of cobalamin

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