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Instead, raised levels may indicate: Liver disease (impaired B12 storage and release) Myeloproliferative disorders or certain leukaemias Renal impairment Recent B12 supplementation or injection Isolated high B12 is usually due to supplementation or binding-protein changes and should be assessed against clinical context and other tests

For instance, initial treatment usually involves intensive residential therapy and support

It can be caused by bile stones, alcohol, or infection

In addition to the benefits listed above, B12 injections can also play an important role in preventing cardiovascular disease, nerve damage, loss of hunger, soreness of the mouth or tongue, poor memory and senile dementia

It appears to modulate neurotransmitter systems, including dopamine and serotonin, and has shown efficacy in counteracting damage induced by various neurotoxins, suggesting potential applications in neurological conditions like Parkinson's disease and schizophrenia-like models