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Hadley King, MD, a board-certified dermatologist in New York

Evidence varies substantially between countries and populations, reflecting differences in study design, reporting practices, legal frameworks, and cultural attitudes toward anabolicandrogenic substance use

doi: 10.4049/jimmunol.1701477 74 GoswamiTKSinghMDhawanMMitraSEmranTBRabaanAAet al

doi: 10.1016/j.exger.2014.03.022 55 TaylorRWTurnbullDM

While the molecular mechanisms of APAP hepatotoxicity are diverse and include different players, including innate immune response, in this review we will focus on the mitochondriallysosomal axis, which has emerged as a novel liason in several pathologies, including lysosomal storage diseases (Torres et al., 2017a), to pinpoint its role in APAP-mediated hepatotoxicity