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FocaccettiCBrunoAMagnaniEBartoliniDPrincipiEDallaglioKet alEffects of 5-fluorouracil on morphology, cell cycle, proliferation, apoptosis, autophagy and ROS production in endothelial cells and cardiomyocytes

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Biswal B, Kunwar P, Natelson BH

Morphologically, it is mainly manifested as ultrastructural changes of mitochondria, such as shrinkage of mitochondria, increased density of mitochondrial membrane, and rupture of mitochondrial cristae and outer membrane