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Antioxidants also indirectly reduce oxidative damage by preventing the expression of enzymes responsible for generating ROS, such as NAD(P)H oxidase and xanthine oxidase, or by promoting the activity or expression of free radical scavengers

A 2023 review found that astaxanthin may reduce inflammation and bone pain

Postprandial serum CPeptide to plasma glucose ratio as a predictor of subsequent insulin treatment in patients with type 2 diabetes

doi: 10.1016/j.survophthal.2022.08.005 43

Additionally, Crohns disease, Celiac disease, and gastric bypass surgery might also affect the absorption rate, thus contributing to the B12 deficiency