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Endoplasmic Reticulum Stress in Neurodegenerative Diseases

For example, Fe 3 O 4 nanoparticles can generate a photothermal effect under light irradiation, promoting tumor cell membrane permeability, enhancing the penetration and action of ferroptosis inducers, and thus effectively killing tumor cells ( As a RIPK1/RIPK3/MLKL axis-driven programmed necrosis, necroptosis is gaining traction in cancer therapeutics through its bifunctional mechanisms: ( + T cell infiltration (Rucker et al., 2024)

Fecal microbiota transplantation combined with prebiotics ameliorates ulcerative colitis in mice

Parkinsonian symptoms can be observed in other pathologies such as Wilsons Disease and Huntingtons Disease (Snyder and Wolozin, 2004

Therefore, elevated GGT expression increases tumor cell resistance to ferroptosis, safeguarding cells from ROS and lipid peroxidation, thus driving tumor cell proliferation, metastasis and chemotherapy drug resistance (85,107)