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A second study of individuals from various European countries with mild Graves orbitopathy found that treatment with selenium at 100 ug twice daily for six months led to improvement of orbitopathy in 61% of participants, as compared with pentoxifylline 600 mg twice daily or placebo, which improved orbitopathy in 35% and 36% of participants, respectively

Many of these components also show antioxidant activity and may help reduce the signs of aging

To test the regeneration potential, a colony formation assay was performed

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