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For the pathogenesis of systemic low-grade inflammation, pro-inflammatory transformation of the endothelium (endotheliosis) acquires particular importance, facilitating atherosclerosis, hypertension, thrombophilia, and microangiopathies [872,873,874,875,876,877]

Author contributions: WX and QZ designed the manuscript

Macrophage recruitment, but not interleukin 1 beta activation, enhances noise-induced hearing damage

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