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TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling

These compounds offer unique therapeutic advantages due to their reversible and targetable nature, enabling precise gene regulation without modifying DNA sequences (325-327)

among them, GPX4 and GSTM1 are overexpressed in BM subsets, and cause massive consumption of GSH in brain metastases of lung cancer ( in vitro and in vivo enhances the anticancer effect of platinum drugs in brain metastatic cells (Luo et al., 2022)

Dengan kemampuan ini, tubuh kita mampu menyerap manfaat dari glutathione dengan lebih lama dan lebih efektif, sehingga bisa meningkatkan kesehatan tubuh dan menekan proses stres oksidatif