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Although some of the physical findings are more commonly observed in ALD (parotid enlargement, Dupuytren's contracture, and especially those signs associated with feminization) than in non-ALD, no single physical finding or constellation of findings is 100% specific or sensitive for ALD

Astrocyte autophagy also modulates neuroinflammation and protein aggregation, influencing AD progression and representing another cellular target to restore proteostasis [116]

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Magnesium has been reported to be essential to the functions of the enzyme gamma glutamyl transpeptidase (GGT), an enzyme that plays an important role in the biosynthesis of glutathione by breaking down circulating extracellular glutathione thus releasing cysteine for intracellular re-assembly of glutathione [10]

Whether it can improve EAE remains undetermined and requires further research in clinical trials