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Spatial organization of protein export in malaria parasite blood stages

-heguelin is a monodesmotic triterpenoid saponin isolated from Hedera nepalensis K.Koch [236], which induces apoptosis at high doses, disrupts the redox system by significantly affecting glutathione metabolism at safe and low toxic doses to induce ferroptosis in NSCLC, and also increases the sensitivity of NSCLC cells to cisplatin [237]

Mov Disord 25(1):117122 Michiels C, Raes M, Toussaint O, Remacle J (1994) Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress

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Unfortunately, although preclinical data show clear-cut neuroprotective effects of luteolin in AD models, there are no human intervention studies or clinical trials investigating its potential beneficial effects in AD patients