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Dato-DXd has shown favorable results in mTNBC patients [261]

The GSH-containing syringe of the stopped-flow spectrofluorometer was supplemented again with 0.4 U/mL GR and 0.25 mM NADPH to remove trace amounts of GSSG and to prevent the thermodynamically favored reverse reaction 32

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The extrinsic pathway involves the activation of a protease cascade intitated by the activation of caspase 8 through the action of death receptors and their ligands, for example, FasL, and tumor necrosis factor- (181)