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Analysis of unfiltered raw data (~35M read average per sample) was completed using the Simple Annotation of Metatranscriptomes by Sequence Analysis 2.0 (SAMSA2) pipeline [21] as follows: PEAR (version 0.9.10) to merge reads, Trimmomatic (version 0.36) to trim low-quality reads, ShortMeRNA (version 2.1) to remove rRNA, and DIAMOND (version 2.0.2) to annotate mRNA data to the RefSeq database [22]

Baseline values for several biomarkers were significantly different between the BH4 and placebo groups

Preclinical studies using intranasally administered dopamine have demonstrated therapeutic effects in two different mouse models of ASD - BTBR and Fmr1 -KO mice [60]

Enjoy it instantly by adding a dessert spoon to yourmilk, juice or yogurtpreferred

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