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doi: 10.1186/s41073-019-0064-8 33 GeXYuJJiangH

Here's the connection with glutathione - people with insulin resistance have been shown to have low levels of the antioxidant which suggests a potential link between this antioxidant and metabolic health

Abbreviations AMPK: AMP-activated protein kinase ARE: Antioxidant response element CBS: Cystathionine beta-synthase CSE: Cystathionase CYST: Cystathionine DCFDA: Dichlorofluoresin diacetate ECAR: Extracellular acidification rate ESI: Electrospray ionization ETC: Electron Transport Chain FCCP: Carbonyl cyanide p-trifluoro-methoxyphenyl hydrazone GSH: Glutathione GSSG: Oxidized glutathione HCY: Homocysteine MAT2A: Methionine adenosyltransferase MTT: 3-(4, 5-Dimethyl-2-tetrazolyl)-2,5-diphenyl-2H tetrazolium bromide assay NAC: N-acetylcysteine Nrf-2: Nuclear factor erythroid-derived 2-like OCR: Oxygen consumption rate OXPHOS: Oxidative phosphorylation ROS: Reactive oxygen species SAM: S-adenosylhomocytseine References Rawla P (2019) Epidemiology of prostate cancer, world

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