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et al., 2016), and induces endothelial nitric oxide synthase (eNOS) expression to exert anti-inflammatory effects (Keitel et al., 2007)

The remaining authors are or were affiliated with Quorum Innovations, LLC

Clin Sci (Lond) 123(7):399416

10.1016/j.redox.2019.101402 128 ZhangJ.ChenS.WeiS.ChengS.ShiR.ZhaoR.et al (2022b)

When ZFN binds to the target gene, FokI will cut the DNA to form a double-strand break, thereby triggering the cells repair mechanism and achieving gene editing (Fig