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In 1889, Charles-Edouard Brown-Squard announced that he had rejuvenated after injecting himself with testicular extracts from guinea pigs and dogs, which he dubbed a rejuvenating elixir. 8 However, it was later shown that the self-administered formulation contained little if any androgen, and the effects were therefore prevalently placebo-dependent

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Minor side effects & safety profile While AOD 9604 appears to have a favorable tolerability profile in early trials, there are still relevant caution points: Reported/mild side-effects Injection-site reactions: redness, swelling, itching, mild pain

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