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111 SapkotaK.MaoZ.SynowickiP.LieberD.LiuM.IkezuT.et al (2016)

Myotubes could be induced to hypertrophy by the PI3K/Akt pathway, which increases protein synthesis and blocks the up-regulation of MAFbx and MuRF1 that occurs during muscle atrophy [54, 59]

These processes are closely interrelated, amplifying each other and contributing to long-term neuronal damage and neurodegeneration

In contrast, research using incremental cycling tests observed increased maximal oxygen uptake and reduced plasma lactate concentrations following LC intake, indicating enhanced aerobic efficiency (Vaz and Wanders 2002)

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