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This disruption results in the translocation of phosphatidylserine from the cytoplasm to the extracellular space, potentially leading to sustained lipid peroxidation of the membrane lipids and ultimately cell death, with CFTR playing a synergistic role in this process

(vii) The amount, if any, by which the specified amount as determined under 427.302(b) exceeds the inflation-adjusted payment amount as determined under 427.302(g) for the Part B rebatable drug for the applicable calendar quarter as set forth in 427.302

J., Neuvonen, P

G., Antel, J