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We reasoned that introducing a leucine zipper motif to the C-terminus of c-MET927 with a short flexible loop (denoted as c-MET927-LZ) could potentially stabilize the c-MET/HGF complex in the active state (Fig

Regulatory Role of Nrf2 Signaling Pathway in Wound Healing Process

Through both distinct and overlapping roles, IL-4 and IL-13 signaling through the IL-4 receptor alpha has shown to affect epidermal barrier dysfunction, increased susceptibility to skin infection, and chronic itch, factors that contribute to the development of eczematous skin lesions