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Pharmacol Biochem Behavior

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Meijer C, Uh H-W, el Bouhaddani S

Of all 30 articles, 7 represented human clinical trials, 22 represented animal studies, and one represented cell culture study

Furthermore, an increased plasma von Willebrand factor is found in hyperhomocysteinemic subjects bearing premature arterial disease (Freyburger et al, 1997) and, of major relevance, acute methionine loading induced moderate hyperhomocysteinemia results in a significant increase in von Willebrand factor (Constant et al, 1999)