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These larger estimates with the MMRM analysis method would be expected since MMRM-based estimates in the SCALE phase 3a trials reflect the treatment effect of liraglutide 3.0 mg after 56 weeks in a hypothetical situation in which all randomized patients were adherent for the planned duration of the trial

Longstanding neurological complications may show limited or incomplete recovery, highlighting the importance of early diagnosis and treatment

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As of 2026, retatrutide has not received marketing authorisation from the MHRA or EMA and is only accessible within authorised clinical trials

Food intolerances, particularly to lactose or fructose, may become more apparent during dietary transitions