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"One patient presented with multisystem involvement with the mucocutaneous lesions being the only clue for the early diagnosis of vitamin B12 deficiency." The study concluded that unexplained and ongoing skin issues might indicate a vitamin B12 deficiency

It affects how blood cells are made

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When B12 levels are too low, people may develop symptoms such as fatigue, weakness, memory problems, or numbness and tingling in the hands and feet