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236 Lifestyle factors, including nutritional therapy, especially the Mediterranean diet, 237 physical activity, 238,239,240 smoking cessation, 241 and quality sleep, are essential for preventing diabetes and its complications

Further optimization and validation on larger patient cohorts are necessary to establish its practical utility in the field

Pharmacological inhibition of COXs significantly reduced MMP-3 and MMP-9 protein expression and enzymatic activity in an in vivo and in vitro model of brain injury can explain the efficacy of COXs inhibitors in protecting against BBB disruption following cerebral ischemia, bacterial meningitis, and against edema associated with brain tumors (Yang C

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Ensures healthy red blood cells Helps with red blood cells formation, essential for warding off anemia. Bolsters frail bones Studies suggest B12 exerts a protective effect on bone density and strength