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Aisa-lvarez A, Prez-Torres I, Guarner-Lans V et al (2023) Randomized clinical trial of antioxidant therapy patients with septic shock and organ dysfunction in the ICU: SOFA score reduction by improvement of the enzymatic and non-enzymatic antioxidant system

Samudio I, Ruvolo P, Konopleva M, Pelicano H, Huang P, Frolova O, Bornmann WG, Y-M Y, Evans R, Younes A, Andreeff M

For example: Endogenous GHRH has a half-life of ~515 minutes Native GLP-1 is broken down in under 2 minutes Thats why natural peptides are rarely used directly in therapeutics theyre too unstable

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