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Studies have shown that nuclear cGAS binds to nucleosomes (mainly H2A-H2B), which prevents the cGAS-DNA binding and cGAS dimerization, thereby maintaining cGAS in an inactive conformation and consequently limiting autoreactivity (3234)

J Clin Oncol 24(5):748-54, 2006

565 Before encountering antigens, naive Th cells rely primarily on FAO and OXPHOS for energy

Regular exercise reduces the expression of A and P-tau proteins in AD mice, enhances brain energy metabolism, restores mitochondrial function, and improves spatial learning and exploratory abilities (Pang et al., 2019)

[DOI] [PMC free article] [PubMed] [Google Scholar] 128.Mentzelou M., Voulgaridou G., Papadimitriou K., Alexatou O., Deligiannidou E.-G., Serdari A., Papadopoulou S.K., Psara E., Tsourouflis G., Giaginis C