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Taking NAC alongside nitroglycerin is strictly contraindicated, as the combination can cause a severe, potentially dangerous drop in blood pressure (hypotension) and intense headaches

The predicted binding position of GSH in the P-pocket of rat Mrp1 is similar to those found by Johnson and Chen [12] for the GS-moiety of LTC4 in bovine Mrp1 resolved by cryo-EM experiments, including hydrogen bond formation to residues R1198 and R1250

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While the body can produce some cysteine on its own using other amino acids like methionine and serine, it is often classified as a conditionally essential amino acid