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Deferoxamine can inhibit iron-induced ferroptosis, and limiting iron intake can alleviate liver damage caused by ferroptosis [54]

additional injections of vitamin B12 on the same day as pemetrexed or pralatrexate treatments as needed

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Because of this challenge to weight maintenance, it is important to develop adjunctive treatments to support patients in achieving their sustained weight-loss goals

Mechanisms and outcomes Vitamin B12 interventions are commenced upon diagnosis of low B12 status, typically comprise high dose injections until levels are within acceptable range, and then the intervention is changed to a maintenance dose that is typically administered every 3 months ad infinitum