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This dual pathway activation allows for investigation of potential synergistic effects between GHRH and ghrelin signaling systems, providing opportunities to study how these complementary mechanisms may work together to optimize growth hormone release patterns

Timing Baseline Marker TSH and free T4 Why it matters Helps separate thyroid-related symptoms from GH-axis effects

GH is secreted by somatotroph cells in the anterior pituitary, which plays a key role in endocrine regulation of GH production and secretion

The abdomen is the most commonly used site and the easiest for self-administration

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