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Roles of Dopamine in Inflammation NLRP3 Inflammasome NLRP3 inflammasome is a group of intracellular multi-protein complexes, participating in the pathogenesis of a variety of diseases, including inflammatory bowel disease, gout, atherosclerosis, and Alzheimers disease (83, 84)

Plaque rupture leads to acute exposure of procoagulant and prothrombotic factors from the necrotic core of the lesion to platelets and procoagulant factors in the lumen, thereby causing thrombus formation (Figure 5) (168,169)

[Mechanism Applicable to Mammalian Systems] Forman HJ, Zhang H, Rinna A

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