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This study further demonstrates the potential of KO to be applied in topical formulations as it can overcome issues related to oral formulations, which is biodistribution and metabolic transformation, and directly target keratinocytes (110)

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identified several risk factors for short-term residual low back pain following percutaneous kyphoplasty, including bone mineral density, preoperative injured vertebral kyphosis, preoperative thoracolumbar fascia injury, cement distribution type, and bone cement filling ratio

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