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This enzymatic activity gave origin to the alternative name of ADH5, GSNOR, proposing it is a protein denitrosylase that can modulate the level of S-nitrosylations by reducing GSNO 48

Abstract GSTP proteins are metabolic enzymes involved in removal of oxidative stress and intracellular signaling and also have inhibitory effects on JNK activity

Ethical clearance Before the study, ethical approval was obtained from the Research and Bioethics Committee of Basic Medical Science, DELSU, Abraka, Delta State, Nigeria (Permit No: REC/FBMS/ DELSU/18/16/53)

Class III FINs, such as FIN56, degrade GPX4 and deplete coenzyme Q10, disrupting cellular antioxidant defenses and promoting ferroptosis 25

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